Gary Gerstenblith's Cardiovascular Disease in the Elderly (Contemporary PDF

By Gary Gerstenblith

A panel of clinicians, researchers, and leaders within the box evaluate and talk about the most recent findings at the pathophysiology, prognosis, and administration of heart problems within the older sufferer. The authors clarify the physiological adjustments linked to the conventional getting older method which may result in the improvement of illness, to hostile effects as soon as affliction develops, and which adjust the risk-benefit equation for scientific and different interventions designed to diagnose, determine, and deal with heart problems. the focal point is on rather universal syndromes within the aged, together with cardiac failure with general ejection fraction, remoted systolic high blood pressure, and atrial traumatic inflammation. anywhere attainable, the authors take an evidence-based method of options and depend seriously on potential medical trials.

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J Hypertens 1999;17:1065–1072. 89. Domanski MJ, Davis BR, Pfeffer MA, Kastantin M, Mitchell GF. Isolated systolic hypertension: prognostic information provided by pulse pressure. Hypertension 1999;34:375–380. 90. Benetos A, Gautier S, Lafleche A, et al. Blockade of angiotensin II type 1 receptors: effect on carotid and radial artery structure and function in hypertensive humans. J Vasc Res 2000;37:8–15. 91. Glynn RJ, Chae CU, Guralnik JM, Taylor JO, Hennekens CH. Pulse pressure and mortality in older people.

Fagard RH, Pardaens K, Staessen JA, Thijs L. The pulse pressure-to-stroke index ratio predicts cardiovascular events and death in uncomplicated hypertension. J Am Coll Cardiol 2001;38:227–231. 96. Domanski MJ, Mitchell GF, Norman JE, et al. Independent prognostic information provided by sphygmomanometrically determined pulse pressure and mean arterial pressure in patients with left ventricular dysfunction. J Am Coll Cardiol 1999;33: 951–958. 97. Neutel JM. Beyond the sphygmomanometric numbers: hypertension as a syndrome.

For example, in a longitudinal study of a large population of relatively aged subjects, increased baseline levels of pulse pressure were associated with progression of IMT, and baseline IMT, in turn, was associated with greater widening of the pulse pressure (137). After all the components of arterial aging are identified, a comprehensive vascular aging profile may be developed 36 Cardiovascular Disease in the Elderly for each individual that represents the integrated sum of all the vascular processes.

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