Evidence-Based Pediatric Oncology - download pdf or read online

By Ross Pinkerton, A. G. Shankar, Katherine Matthay

This ebook is up-to-date with proof from the newest released studies and is extra clinically concentrated, with an emphasis on software of the trial findings. With elevated assurance of trials within the sector of supportive take care of pediatric melanoma sufferers, each one bankruptcy opens with a scientific query and concludes with a precis at the trial findings from knowledgeable commentator.

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8 Bacci G, Picci P, Ruggieri P et al. Primary chemotherapy and delayed surgery (neoadjuvant chemotherapy) for osteosarcoma of the extremities. Cancer 1990;65:2539–53. 9 Winkler K, Bielack S, Delling G et al. Effect of intraarterial versus intravenous cisplatin in addition to systemic doxorubicin, high dose methotrexate, and ifosfamide on histologic tumour response in osteosarcoma (study COSS-86). Cancer 1990;66:1703–10. 10 Souhami RL, Craft AW, van der Eijken JW et al. Randomized trial of two regimens of chemotherapy in Chapter 2: Osteosarcoma operable osteosarcoma: a study of the European Osteosarcoma Intergroup.

2011;47(16):2431–45. 15 Meyers P, Gorlick R, Heller G et al. Intensification of ­pre-operative chemotherapy for osteogenic sarcoma: results of the Memorial Sloan-Kettering (T12) protocol. J Clin Oncol 1998;16:2452–8. 16 Jaffe N, Robertson R, Ayala A et al. Comparison of intraarterial cis-diamminedi-chloroplatinum II with high-dose methotrexate and citrovorum factor rescue in the treatment of primary osteosarcoma. J Clin Oncol 1985;3:1101–4. 17 Winkler K, Bielack S, Delling G et al. Effect of intraarterial versus intravenous cisplatin in addition to systemic doxorubicin, high dose methotrexate, and ifosfamide on histologic tumour response in osteosarcoma (study COSS-86).

3 Edmonson JH, Green SJ, Ivins JC et al. A controlled pilot study of high-dose methotrexate as postsurgical adjuvant treatment for primary osteosarcoma. J Clin Oncol 1984;2:152–6. 4 Link MP, Goorin AM, Miser AW et al. The effect of adjuvant chemotherapy on relapse-free survival in patients with osteosarcoma of the extremity. N Engl J Med ­ 1986;314:1600–6. 5 Eilber F, Giuliano A, Eckardt J, Patterson K, Moseley S, Goodnight J. Adjuvant chemotherapy for osteosarcoma. A randomised prospective trial.

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