By S. Fedoroff (auth.), Hans H. Althaus, Wilfried Seifert (eds.)
This accomplished quantity is a contribution to a brand new se ries initiated through the NATO Panel on "Gell to Gell indications in crops and Animals". The ebook displays the result of an NATO paintings store and bri ngs to mi nd im portant questions: consideri ng the mass of correct I iteratu reavai- capable, is there any necessity for a brand new sequence of books - and contemplating the flood of compa rable conferences - is there any aspect in workshops of this nature and their ebook? so as to care for such questions correctly, even more area will be wanted than comes in a foreword. hence, the solutions needs to stay relatively superficial and, in fact, quite subjective. To simplify the difficulty, the query of book may be narrowed all the way down to fac tors - the monetary danger, undertaken via the writer, and the medical possibility, borne by way of the editor. If the e-book is nice (with admire to lay-out and content material) will probably be a hit - not anything should be misplaced the folk concerned will improve their recognition! we're left with the query of the usefulness of workshops. absolutely, it really is certainly an invaluable technique for specialists to return jointly, in an environment of concord, and freedom from exterior pressures and time barriers, to debate a well-defined subject. Wether in contract or confrontation, a good and open discussion board will be expectet for a number of contributions.
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Extra info for Glial-Neuronal Communication in Development and Regeneration
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Abstr. 8 p. 939. 86) QUINLAN, R. A. and FRANKE, W. W. (1983). Molecular interactions in intermediate-sized lilaments revealed by chemical cross-linking. Eur. J. , 132,477 - 484. 87) RAFF, M. , FIELDS, K. , HAKOMORI, S. , PRUSS, R. M. and WINTER, J. (1979). Cell type specilic markers lor distinguishing and studying neurons and the major classes 01 glial cells in culture. , 174,283 - 308. 88) RAFF, M. , ABNEY, E. , L1NDSAY, R. and NOBLE, M. (1983). Two types 01 astro- cytes in cultures 01 developing rat white matter: dillerences in morphology, surface gangliosides, and growth characteristics.
1979. , 1984. , 1984. , 1982. , 1983. Hertz, 1982. 17 G03 ganglioside is not expressed on either mature neurons or astrocytes (36), but Tt binding gangliosides are expressed on neurons throughout development and postnatally (87) and on subpopulations of astrocytes postnatally (88). In our laboratory we have observed that the Tt binding sites, as weil as binding sites for the A2B5 monoclonal antibody (wh ich also is a polysialoganglioside) (20), appear on fibrous astrocytes only in older cultures (51).
The parts of the membrane apposed to blood vessels or cerebrospinal fluid have higher accumulations of assemblies and parts ofthe membrane ofthe processes that invest the neurons have markedly fewer (63). Astrocytes in older cultures also have assemblies which are not distributed uniformly. The distribution of assemblies in cultures is not related to the substratum or to culture medium (1, 65). The function of assemblies is unknown. The fact that their distribution is related to the juxtaposition of the membranes to blood vessels or cerebrospinal fluid suggests that the assemblies represent sites at wh ich some material is transported across the membrane at the interface with blood and cerebrospinal fluid compartments (64).
