By Gerhardus de Jong
This monograph deals the reader an entire evaluation on either rules and purposes of CE-MS. beginning with an introductory bankruptcy on detection in CE, additionally similar and extra really expert strategies resembling electrophoretic and chromatographic preconcentration are mentioned. a different emphasis is wear CE-MS interfaces, that are defined intimately. In a separate bankruptcy, recognition is paid to sheath-liquid interfacing. The advancements and chances of microchip CE-MS also are defined. purposes to all correct components are mentioned in targeted chapters, every one written by means of specialists within the respective fields.
along with functions in pharmaceutical research and bioanalysis, fresh implementations in nutrition technological know-how, forensic research, research of intact proteins, metabolomics and proteomics are highlighted. MS is a superbly applicable detection method for CE, as effective separation is coupled to delicate and choice detection. furthermore, MS offers constitution info at the separated compounds. CE-MS has now been constructed right into a powerful hyphenated method complementary to LC-MS. This monograph is an exact resource of information for everybody facing and drawn to CE-MS
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Extra resources for Capillary Electrophoresis - Mass Spectrometry (CE-MS) Principles and Applications
Example text
Despite the large number of applications, most of the interfaces presented here are in use by only one or two research groups. Only one of these interfaces (CESI 8000, AB SCIEX) is commercialized and is therefore more widespread in use, yet there has been significant growth in the field of CE-MS. Future commercialization of other CE-MS interfaces would allow for more widespread use by giving options for choosing an interface best suited for the kind of analysis one plans to do. In time, interfaces such as those presented in this chapter may begin to replace the coaxial sheathliquid interface, which is still a standard interface used for many CE-MS applications.
A. L. (2004) Capillary Electrophoresis of Proteins and Peptides, Humana Press, Totowa, NJ. B. (2009) Atmospheric pressure ion sources. Mass Spectrom. , 28, 870–897. R. (1988) Improved electrospray ionization interface for capillary zone electrophoresis-mass spectrometry. Anal. , 60, 1948–1952. Y. (2011) Mass transport in a micro flow-through vial of a junction-atthe-tip capillary electrophoresis–mass spectrometry interface. Anal. , 83, 4916–4923. Y. (2011) Flow-through microvial facilitating interface of capillary isoelectric focusing and electrospray ionization mass spectrometry.
84. 85. 86. profiling of intact pharmaceutical proteins. Anal. , 85, 2289–2296. Y. (2012) Monitoring potential prostate cancer biomarkers in urine by capillary electrophoresis–tandem mass spectrometry. J. Chromatogr. A, 1267, 162–169. , and Li, L. (2015) Relative quantification of amine-containing metabolites using isobaric N,N-dimethyl leucine (DiLeu) reagents via LC-ESI-MS/MS and CE-ESI-MS/MS. Analyst, 140, 467–475. , and Hankemeier, T. (2014) Capillary electrophoresis–mass spectrometry using a flow-through microvial interface for cationic metabolome analysis.
